RecruitingNot ApplicableNCT05932745

Effects of Novel E-cigarette Constituents on Adults TCORS 3.0

Examining Appeal and Addiction Potential of Novel E-cigarette Constituents Among Adults

Sponsor

Yale University

Enrollment

66 participants

Start Date

Jun 20, 2025

Study Type

INTERVENTIONAL

Conditions

Nicotine Use Disorder

Summary

This study is an examination of the influence of cooling components of WS-3, WS-23, and menthol on the appeal and addiction potential of nicotine-containing e-liquids among adults.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying E-liquid coolant (4% WS-23) for high (2.0%) menthol (6), E-liquid coolant (4% WS-23) for low (0.1%) menthol (6), and others for people with nicotine use disorder. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERE-liquid coolant (No WS-3) for non-menthol (1)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants without WS-3.

OTHERE-liquid coolant (No WS-3) for low (0.1%) menthol (1)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants without WS-3.

OTHERE-liquid coolant (No WS-3) for high (2.0%) menthol (1)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants without WS-3.

OTHERE-liquid coolant (Low [0.1%] WS-3) for non-menthol (2)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-3 concentration.

OTHERE-liquid coolant (Low [0.1%] WS-3) for low (0.1%) menthol (2)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-3 concentration.

OTHERE-liquid coolant (Low [0.1%] WS-3) for high (2.0%) menthol (2)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-3 concentration.

OTHERE-liquid coolant (High [2.0%] WS-3) for non-menthol (3)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-3 concentration.

OTHERE-liquid coolant (High [2.0%] WS-3) for low (0.1%) menthol (3)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-3 concentration.

OTHERE-liquid coolant (High [2.0%] WS-3) for high (2.0%) menthol (3)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-3 concentration.

OTHERE-liquid coolant (Low [0.1%] WS-23) for non-menthol (4)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-23 concentration.

OTHERE-liquid coolant (Low [0.1%] WS-23) for low (0.1%) menthol (4)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-23 concentration.

OTHERE-liquid coolant (Low [0.1%] WS-23) for high (2.0%) menthol (4)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-23 concentration.

OTHERE-liquid coolant (High [2.0%] WS-23) for non-menthol (5)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-23 concentration.

OTHERE-liquid coolant (High [2.0%] WS-23) for low (0.1%) menthol (5)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-23 concentration.

OTHERE-liquid coolant (High [2.0%] WS-23) for high (2.0%) menthol (5)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-23 concentration.

OTHERE-liquid coolant (4% WS-23) for non-menthol (6)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with 4% WS-23 concentration.

OTHERE-liquid coolant (4% WS-23) for low (0.1%) menthol (6)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with 4% WS-23 concentration.

OTHERE-liquid coolant (4% WS-23) for high (2.0%) menthol (6)

Adult users of e-cigarette will be exposed to distinct e-liquid coolants with 4% WS-23 concentration.

Locations(1)

JB Pierce Lab

New Haven, Connecticut, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05932745

Related Trials

Temporal Interference Methods for Addiction Treatment

NCT072102682 locations

Implementation of Tobacco Cessation Programming at Community Behavioral Health Sites

NCT068372201 location

Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking

NCT051818911 location

Testing the Feasibility and Acceptability of Social Media and Digital Therapeutics to Decrease Vaping Behaviors

NCT059942091 location

Smoking Cessation and Menstrual Cycle Phase

NCT055153541 location