Impulsivity With Borderline Personality Disorder/tMS
Reduction of Impulsivity in Patients With Borderline Personality Disorder Using Dual-site Transcranial Magnetic Stimulation
Hôpital le Vinatier
40 participants
Jan 8, 2024
INTERVENTIONAL
Conditions
Summary
This is a prospective, randomized, double-blind, parallel-group controlled trial. The aim of this research project is to compare the clinical benefits achieved in patients with Borderline Personality Disorder (BPD) following two types of intervention: ccPAS active or ccPAS sham.
Eligibility
Inclusion Criteria1
- Diagnosis of BPD (established by a psychiatrist and confirmed in a structured interview using the MINI) based on the Diagnostic and Statistical Manual of Mental Disorders (DSM V).
Exclusion Criteria5
- Contraindications to TMS/MRI (pacemakers or other devices likely to interfere with the magnetic field).
- Pregnant or breast-feeding women.
- Ongoing anxiolytic treatment (benzodiazepines), neuroleptic treatment or anticonvulsants acting on GABAergic transmission ; 24 hours prior to the protocol.
- Diagnosis of other chronic psychiatric pathology including bipolar disorder type I or II and addictions (except tobacco).
- Protective measure (curatorship or guardianship)
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
The first stimulation will be applied to the IFC and the second to the pre-SMA, with an interstimulation interval set at 4 ms. A total of 180 stimulation pairs will be delivered every 2 s. (5Hz) for a total duration of 15 minutes at an intensity of 120% of rMT
The first stimulation will be applied to the IFC and the second to the pre-SMA, with an interstimulation interval set at 100 ms. A total of 180 stimulation pairs will be delivered every 2 s. (5Hz) for a total duration of 15 minutes at an intensity of 120% of rMT
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05942651