RecruitingNCT05944640

Dynamic Parameters of Glucose Control in Relation to Biomarkers in Serum and Intraocular Fluid in Patients With Diabetes

Dynamic Parameters of Glucose Control in Relation to Biomarkers in Serum and Intraocular Fluid in Diabetic Patients With Ocular Complications

Sponsor

Charles University, Czech Republic

Enrollment

213 participants

Start Date

Apr 1, 2022

Study Type

OBSERVATIONAL

Conditions

Diabetes Complications

Summary

Our project investigates the new characteristics of diabetic retinopathy using liquid eye biopsy in combination with novel parameters of glucose control obtained with continuous glucose monitoring. This approach will bring new knowledge and implications for future therapies.

Eligibility

Min Age: 18 Years

Inclusion Criteria6

type 1 or type 2 diabetes
≥ 18 years old
treatment with insulin for at least 5 years prior baseline
any form of diabetic retinopathy and macular edema
HbA1c < 10%
written informed consent prior to starting study related activity

Exclusion Criteria5

any active intraocular or periocular infectious or non-infectious inflammation in study eye
uncontrolled glaucoma
history of intraocular inflammation or trauma in study eye
intravitreal anti-VEGF therapy in study eye during a 3-month perido prior to baseline
use of corticosteroid intravitreal implant in study eye at any time

Interested in this trial?

Get notified about updates and connect with the research team.