RecruitingNCT05951114

Post-neurosurgical Respiratory Muscle Dysfunction

The Development of Post-operative Respiratory Muscle Dysfunction in Neurosurgical Patients


Sponsor

Beijing Sanbo Brain Hospital

Enrollment

100 participants

Start Date

Jul 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

Respiratory muscle dysfunction may contribute to the development of postoperative pulmonary complications. However, it prevalence in patients receiving neurosurgery is largely unknown. Therefore, in present study, respiratory muscle function (measured by the ultrasound) and their correlation with the post-operative pulmonary complications will be analyzed.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Informed consent
  • First elective operation during hospitalization
  • ASA\<3

Exclusion Criteria9

  • Brain stem and spinal spine lesions
  • Preoperative chest imaging findings were abnormal
  • Mechanical ventilation was required before surgery
  • Clinical or radiological evidence of preoperative misaspiration
  • History of neurosurgery in the last 6 months
  • A history of neuromuscular disease
  • BMI≥35kg/m2
  • Pregnant women
  • Skin lesions detected by ultrasound

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Interventions

DIAGNOSTIC_TESTMaximum inspiratory/Expiratory manoeuvre for patients can follow the order

Bedside ultrasound will be performed for each patient at the time before, after surgery, before and after extubation, and at the time of ICU discharge, under the end-expiratory occlusion, maximum inspiratory, and/or expiratory manoeuvre


Locations(1)

Beijing Sanbo Brain Hospital, Capital Medical University

Beijing, Beijing Municipality, China

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NCT05951114


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