Presacral Nerve Block Versus Sham Block on Post-operative Pain for Total Laparoscopic Hysterectomy
A Randomized Controlled Trial (RCT) Comparing Presacral Nerve Block Versus Sham Block on Post-operative Pain in Women Undergoing Total Laparoscopic Hysterectomy.
Mount Sinai Hospital, Canada
60 participants
Sep 24, 2025
INTERVENTIONAL
Summary
The study is a single-center parallel group randomized controlled trial comparing the administration of a presacral nerve block using 20mL of local ropivacaine 5.0mg/ml versus 20mL of normal saline (sham block) on post-operative pain following total laparoscopic hysterectomy.
Eligibility
Inclusion Criteria2
- years of age or older
- Undergoing total laparoscopic hysterectomy
Exclusion Criteria8
- Previous presacral neurectomy
- Concurrent surgical procedure other than salpingectomy and/or oophorectomy
- Gynecological cancer beyond stage 1 disease
- BMI > 50
- Chronic opioid consumption
- Fibromyalgia
- Language barrier
- Inability to communicate and provide consent
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Interventions
Presacral nerve block using 20mL of local ropivacaine 5.0mg/ml
Sham block using 20 mL of normal saline (0.9% sodium chloride)
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05953766