RecruitingNot ApplicableNCT05961800

Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks

OMEGA Study: Offset Mechanisms in Evaluation of Lumbar Medial Branch Block


Sponsor

University of Pittsburgh

Enrollment

40 participants

Start Date

Jul 5, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This study examines the relationship between central nervous system (CNS) mechanisms of pain inhibition and the pain relief that occurs following a lumbar medial branch block (MBB).


Eligibility

Min Age: 18 Years

Inclusion Criteria6

  • Scheduled for lumbar MBB in UPMC Pain Management clinics
  • Age \> 18 years old
  • Predominantly axial chronic low back pain at least 3 months on a daily basis
  • Must meet the minimum criteria for cognitive function using the PROMIS 2-item cognitive screener (\>3)
  • Low back pain intensity of \> 3/10
  • Willing and able to receive study-related phone calls

Exclusion Criteria5

  • History of spine surgery at the level of the lumbar MBB
  • Active worker's compensation or litigation claims
  • New pain and/or psychiatric treatments within 2 weeks of enrollment
  • Not fluent in English and/or not able to complete the questionnaires
  • Any clinically unstable systemic illness that is judged to interfere with the study

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Interventions

BEHAVIORALCutaneous Probe

A computer-controlled probe delivers temperatures to the skin to measure pain, offset analgesia and onset hyperalgesia.

BEHAVIORALQuantitative Sensory Testing

Standard methods involving pinprick, pressure, heat, and cold applied to the skin are used to measure sensation and pain

BEHAVIORALComputer Tasks

Quantitative Sensory Testing (QST) and computer tasks are used to measure changes in pain intensity.


Locations(1)

UPMC St. Margaret

Pittsburgh, Pennsylvania, United States

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NCT05961800


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