RecruitingNot ApplicableNCT05962164

Passive Heat Therapy for People With COPD

The Acute and Chronic Benefits of Passive Heat Therapy for People With COPD


Sponsor

University of British Columbia

Enrollment

32 participants

Start Date

Aug 17, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

People with Chronic Obstructive Pulmonary Disease (COPD) often develop high blood pressure and heart disease due to their sedentary lifestyle and difficulty exercising. The investigators will test if heating can mimic the health benefits of exercise by monitoring the increase in leg blood-flow using ultrasound during a 45-minute hot-water footbath. The patients will then undergo 6-weeks of hot-water footbaths to examine whether the changes to blood-flow lead to improvements in blood pressure and other indicators of heart disease risk.


Eligibility

Min Age: 40 Years

Inclusion Criteria3

  • Non-smoking individuals
  • \>40 years of age
  • Stable (exacerbation free for \>6 weeks), moderate-to-severe COPD (post bronchodilator FEV1/FVC \<lower limit of normal and FEV1 z-score \<2.51)

Exclusion Criteria9

  • Performing structured exercise training (i.e. pulmonary rehabilitation)
  • Have advanced cardiac or cerebrovascular disease (i.e. a history of heart failure, previous stroke or myocardial infarction)
  • Have uncontrolled hypertension (\>160/95 mmHg at rest)
  • Have hypotension (\<110/60 mmHg)
  • Are taking Beta Blockers
  • Regularly (\>1/week) have hot baths (\>30 min) or use a hot tub or sauna.
  • Have resting blood pressure \> 150/95 mmHg
  • On supplemental oxygen for hypoxemia.
  • Musculoskeletal pain that limits their ability to perform stationary cycling.

Interventions

BEHAVIORALPassive Heat Therapy

The intervention will consist of 6 weeks of repeated (3x/week) 45-min lower-leg immersions.

BEHAVIORALSham Immersion

The sham intervention will consist of 6 weeks of repeated (3x/week) 45-min lower-leg immersions.


Locations(1)

University of British Columbia

Kelowna, British Columbia, Canada

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NCT05962164


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