RecruitingNot ApplicableNCT05973110

Examining the Efficacy of a Virtual Reality Cognitive Remediation Program for People Living With Psychosis


Sponsor

The Royal Ottawa Mental Health Centre

Enrollment

52 participants

Start Date

Jul 31, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Individuals living with a psychotic disorder often experience changes to their thinking and social skills that can lead to challenges with work, school, relationships and living independently. One intervention to target these areas is cognitive remediation therapy, which can be delivered in virtual reality to help apply the skills and strategies learned to day-to-day life. Over the past few years, our team has co-developed a cognitive remediation program in virtual reality with healthcare professionals and people with lived experiences of psychosis. The current trial tests the feasibility and efficacy of this cognitive remediation program in virtual reality at improving thinking skills, social skills, and daily life functioning.


Eligibility

Min Age: 18 YearsMax Age: 60 Years

Inclusion Criteria5

  • Diagnosis of a psychosis-spectrum disorder
  • Equal or between 18 to 60 years old
  • Ability to read and speak English
  • Be clinically stable, as defined as a total Positive And Negative Severity Symptoms score equal or between 30 - 95
  • No changes to their medication dosage, starting a new medication, or stopping a medication within the past month before signing the consent form

Exclusion Criteria6

  • Neurological or medical disorders that may produce cognitive impairment (including head injury with more than 1 minute of loss of consciousness)
  • Intellectual disability or a score equal or below 70 on the Wechsler Abbreviated Scale of Intelligence.
  • Any vision conditions that cannot be corrected with contact lenses or glasses that can fit in the virtual reality googles.
  • Past history of seizures, fit, and epilepsy
  • Any severe medical condition related to the eyes, ears, and balance
  • History of substance use disorder within the last 3 months

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Interventions

BEHAVIORALCognitive Remediation

In each of the 12 visits, participants will complete exercises in virtual reality for two sessions of about 15 minutes separated by a break of 5 to 10 minutes. Participants then engage in a bridging conversation with study staff for about 15 minutes. More details about each condition will be added after study completion to protect the blinding of our participants.

BEHAVIORALActive Control

In each of the 12 visits, participants will complete exercises in virtual reality will complete exercises in virtual reality for two sessions of about 15 minutes separated by a break of 5 to 10 minutes. Participants then engage in a bridging conversation with study staff for around 10 to 15 minutes. More details about each condition will be added after study completion to protect the blinding of our participants.


Locations(1)

Royal Ottawa Mental Health Centre

Ottawa, Ontario, Canada

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NCT05973110


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