RecruitingNot ApplicableNCT05975606

Non-invasive Brain Stimulation Paired With FES Cycling Post SCI

Exploring the Effect of Non-invasive Brain Stimulation Paired With Functional Electrical Stimulation to Improve Lower Extremity Function Following Incomplete Spinal Cord Injury


Sponsor

Western University, Canada

Enrollment

14 participants

Start Date

Sep 19, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This project is randomized controlled trial which will explore the effect of pairing repetitive Transcranial Magnetic Stimulation (rTMS) with Functional Electrical Stimulation (FES) Cycling on lower extremity function in people with incomplete spinal cord injury and compare the effects to each one of these interventions alone.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • adult
  • having motor incomplete SCI with level C or D on the American Spinal Injury Association Impairment Scale (AIS) with the lesion at any level of the cord resulting from either traumatic or non-traumatic etiology who are at least one-year post-injury.
  • having non-progressive SCI
  • being able to walk independently for 10 meters without help from another person

Exclusion Criteria3

  • other orthopedic or neurological implications that affect the lower extremity function
  • contraindications to FES (e.g., implanted electronic devices, unhealed bone fractures, sever contractures, extreme osteoporosis or osteoarthritis)
  • contraindications to rTMS (e.g., metal implants, history of seizure, cochlear implants)

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Interventions

DEVICErepetitive transcranial magnetic stimulation (rTMS)

rTMS will be applied to primary motor cortex of the brain.

DEVICEfunctional electrical stimulation (FES) cycling

FES will be applied to muscles associated in cycling: quadriceps, hamstrings, tibialis anterior, gastrocnemius, soleus.


Locations(1)

Parkwood Institute

London, Ontario, Canada

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NCT05975606


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