RecruitingNCT05977621

Trans-Rectal Ultrasound of the Female Pelvis for Real-Time MRI-US Fusion Based Needle Tracking

Acquisition of Trans-Rectal Ultrasound [TRUS] Images of the Female Pelvis for Real-Time MRI-US Fusion Based Needle Tracking for Image-Guided Brachytherapy: A Pre-feasibility Study


Sponsor

Duke University

Enrollment

17 participants

Start Date

Feb 7, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to utilize transrectal ultrasound (TRUS) images of the intact and post-hysterectomy female pelvis in order to provide feasibility information for a Magnetic Resonance Imaging (MRI)-TRUS fusion based 3D needle navigation system for use in image guided brachytherapy. The fusion and needle guidance will be performed using Eigen Health's navigation system that currently provides targeted MR/Ultrasound fusion based prostate biopsies utilizing a proprietary 3D semi-robotic navigation system.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study is developing a real-time MRI-guided system for tracking needles during brachytherapy (internal radiation) for cervical or uterine cancer. The goal is to improve the precision of needle placement to deliver radiation more accurately to the tumor. **You may be eligible if...** - You are 18 or older - You have been diagnosed with invasive cervical cancer, or recurrent/inoperable uterine cancer - Your treatment plan includes internal radiation therapy (brachytherapy), with or without chemotherapy - You are in good enough health for these treatments (ECOG performance status 0–2) **You may NOT be eligible if...** - You have active rectal bleeding or a rectal ulcer that would make the procedure unsafe Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERTransrectal ultrasound (TRUS)

Transrectal ultrasound (TRUS) images of the female pelvis


Locations(1)

Duke Cancer Center

Durham, North Carolina, United States

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NCT05977621


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