Sample Collection for Ongoing Research and Product Evaluation Study

This study is collecting blood and tumor tissue samples from people with newly diagnosed cancers to support ongoing research into early cancer detection and treatment response monitoring. **You may be eligible if...** - You are 18 or older - You have an untreated primary solid cancer in one of these categories: breast, lung, bladder (muscle-invasive), rectal, pancreatic, ovarian, gastroesophageal, prostate, melanoma, liver, uterine/endometrial, or head and neck cancer - OR you are suspected to have pancreatic, endometrial, bladder, or ovarian cancer based on imaging - You are in good enough physical condition (ECOG 0–2) to have a blood draw and agree to share residual tumor tissue **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have had or been treated for another cancer in the past year - You have already started treatment for your current cancer - You have a history of bone marrow or organ transplant Talk to your doctor to see if this trial is right for you.