RecruitingNot ApplicableNCT05978388

Coronary Computed Tomography AngioGraphy Prior to Catheter Ablation in Patients With Atrial FIBrillation


Sponsor

Tor Biering-Sørensen

Enrollment

852 participants

Start Date

Mar 26, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this randomized, controlled trial is to investigate whether coronary computed tomography (CT) angiography prior to catheter ablation and derived treatment (medical anti-ischemic and multimodality treatment and/or mechanical revascularization) can improve clinical outcomes in patients with atrial fibrillation undergoing catheter ablation. A sub-study will investigate the effect of different ablation strategies on clinical outcomes in patients with atrial fibrillation undergoing catheter ablation.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Age over 18 years.
  • Referral for catheter ablation treatment (excluding AV-junction ablation) for atrial fibrillation (both paroxysmal and persistent atrial fibrillation) at the Department of Cardiology at Gentofte Hospital. Both first ablation and re-ablation treatments are included.
  • The ability and willingness to provide written informed consent.

Exclusion Criteria5

  • Known atherosclerotic cardiovascular disease (ASCVD).
  • Ongoing treatment with statins.
  • Contraindications for coronary CT angiography, e.g. contrast allergy
  • Recent coronary CT angiography including CAC-score without positive findings \<3 years prior to screening.
  • Any surgical or medical condition, which in the opinion of the investigator, may place the patient at higher risk from his/her participation in the study, or is likely to prevent the patient from complying with the requirements of the study or completing the study.

Interventions

DIAGNOSTIC_TESTAnalysis of coronary CT Angiography and CAC scoring at the time of catheter ablation

Analysis of coronary CT angiography and CAC scoring and initiation of relevant derived treatment at the time of catheter ablation.


Locations(1)

Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte

Hellerup, Capital Region, Denmark

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05978388


Related Trials