RecruitingNCT05982847

National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South Africa

National Blood Pressure Screening in Children to Optimise Clinical Management of Paediatric Hypertension in South Africa


Sponsor

North-West University, South Africa

Enrollment

22,464 participants

Start Date

Apr 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The Childhood Hypertension Consortium of South Africa (CHCSA) was established to foster relationships between the healthcare sector and schools through community engagement and outreach as well as contributing to the decolonization of normative paediatric blood pressure reference values. To date, there has been no nation-wide project in South Africa to determine nationally representative normal blood pressure reference values, nor to estimate the true prevalence of hypertension in the paediatric population of the country. This study will provide critical information on the understanding of blood pressure and hypertension in children, especially of African ancestry. Not only will this effort contribute to the development of the first nationally representative normal reference values of blood pressure but will also benefit healthcare providers in the sector with a clear guideline on the management of high blood pressure in children as developed by experts working with these challenges daily.


Eligibility

Min Age: 5 YearsMax Age: 18 Years

Inclusion Criteria2

  • All children between ages 5-\<18 years
  • All children with voluntary assent/consent and parent's permission

Exclusion Criteria5

  • circumstances interfere with the participant's ability to give informed consent (diminished understanding or comprehension, or any language barriers that may pose potential risk in participation under false expectations)
  • randomly selected children who choose not to participate (lack of assent/consent), even if parent's permission was received,
  • conditions that interfere with a patient's ability to follow study guidelines, e.g., the use of drugs, alcohol or tobacco products
  • ages \>18 years or under 5 years
  • Children will be excluded from the analysis for the determination of normative reference values for blood pressure and anthropometry if taking certain concomitant medication(s) that may affect their blood pressure, or any underlying disease e.g., chronic kidney disease, chronic heart disease etc. that may raise blood pressure.

Interventions

DIAGNOSTIC_TESTBlood pressure screening

Blood pressure and anthropometric measurements will be performed in children and adolescents between ages 5-18 years to develop South African nomograms that will aid in the development of clinical practice guidelines to optimise hypertension care in South Africa youth.


Locations(11)

Walter Sisulu University

Mthatha, Eastern Cape, South Africa

Nelson Mandela Metropolitan University

Port Elizabeth, Eastern Cape, South Africa

University of the Free State

Bloemfontein, Free State, South Africa

University of the Witwatersrand

Johannesburg, Gauteng, South Africa

University of KwaZulu-Natal

Durban, KwaZulu-Natal, South Africa

University of Limpopo

Polokwane, Limpopo, South Africa

Hypertension in Africa Research Team (HART), North-West University

Potchefstroom, North West, South Africa

Red Cross War Memorial Children Hospital

Cape Town, Western Cape, South Africa

South African Medical Research Council

Cape Town, Western Cape, South Africa

University of Cape Town

Cape Town, Western Cape, South Africa

University of Zurich

Zurich, Switzerland

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05982847


Related Trials