RecruitingNot ApplicableNCT05990244

Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion

Comprehensive Assessment of Tumor Stiffness and Adhesion in Glioma Using Magnetic Resonance Elastography: A Prospective Study

Sponsor

Shengjing Hospital

Enrollment

100 participants

Start Date

Jan 1, 2017

Study Type

INTERVENTIONAL

Conditions

Glioma

Summary

this study will investigate the relationship between tumor stiffness and adhesion in gliomas using MRE. By utilizing preoperative MRE and Intraoperative neuronavigation, followed by comprehensive molecular pathology analysis, we aim to explore the correlation of tumor stiffness and adhesion with molecular and genetic characteristics of gliomas. Additionally, the predictive value of MRE in terms of pathological staging and prognosis will be determined. This research may pave the way for improved clinical decision-making, personalized treatment approaches, and more accurate clinical trials for glioma patients.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study uses a special MRI technique called magnetic resonance elastography (MRE) — which measures tissue stiffness — to better understand glioma (brain tumor) properties before surgery, potentially helping surgeons predict how difficult a tumor will be to remove. **You may be eligible if...** - You are older than 18 - You have a brain tumor (glioma) with a diameter larger than 2 cm - You are in generally good health (Karnofsky score above 60) - You can undergo the MRE scan within one week before surgery **You may NOT be eligible if...** - You have already received treatment for glioma (prior surgery, radiation, or chemotherapy) - You are unable to complete the MRE scan due to claustrophobia, vibration discomfort, or poor image quality Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTMagnetic Resonance Elastography

Undergo MRE and routine MRI

PROCEDUREAssessment and Recording

Undergo recording of tumor stiffness during surgery and molecular pathological classification through genetic analysis

Locations(1)

Shengjing Hospital

Shenyang, Liaoning, China

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NCT05990244

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