A Population-based, Multicenter Cohort Study of Combined Screening for Gastrointestinal Tumors

Exclusion Criteria10

• \. History of any type of malignancy 2. Previous resection of esophagus, stomach or colorectal 3. Received gastrointestinal endoscopy such as colonoscopy and gastroscopy in recent 5 years 4. Have received fecal occult blood test and fecal DNA test in the past 1 year. 5. Contraindications to endoscopy. 6. Warning symptoms of digestive tract tumors, including:
• Difficulty swallowing, choking or halting feeling when eating recently
• Recent esophageal foreign body sensation or swallowing pain
• Recent long-term loss of appetite and appetite
• Recent and prolonged symptoms of indigestion (including acid reflux, heartburn, abdominal grumbling, burping, nausea or premature satiety, etc.)
• Recent symptoms of abdominal mass, abdominal pain, vomiting or hematemesis
• It was medically diagnosed as iron deficiency anemia
• Recent changes in hematochezia, black stool or stool character and frequency
• Recent symptoms of perianal discomfort (including soreness, itching, lumps, prolapse or other discomfort)
• Unexplained weight loss (more than 10% of base body weight) in the past 6 months Step 7 Get pregnant 8. There are other serious comorbiditions that reduce screening benefits (including severe lung disease, advanced kidney disease, advanced liver disease, severe heart failure, etc.)