RecruitingNot ApplicableNCT06000475

Enhancing Memory in CPT for PTSD

Enhancing Memory in Cognitive Processing Therapy for Older Adults With PTSD


Sponsor

VA Office of Research and Development

Enrollment

30 participants

Start Date

Oct 15, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Several psychotherapies for posttraumatic stress disorder (PTSD) have a strong evidence base for their efficacy, but nonresponse rates are high, particularly among older Veterans. Accumulating evidence indicates that memory deficits and poor learning of therapy contents adversely affect psychotherapy treatment response in PTSD. However, limited research has examined methods for increasing learning of therapy contents in psychotherapy for PTSD. The proposed study aims to examine the feasibility of integrating an intervention to increase learning and memory of psychotherapy content into the provision of a widely used psychotherapy, cognitive processing therapy (CPT), for older adults with PTSD. The ultimate goal of this line of research is to develop novel rehabilitation interventions to increase functioning for individuals with PTSD.


Eligibility

Min Age: 60 Years

Inclusion Criteria2

  • Veterans with DSM-5 diagnoses of PTSD via the Clinician Administered PTSD Scale (CAPS-5)
  • Age \>59

Exclusion Criteria7

  • daily benzodiazepine use (due to memory impairing effects)
  • bipolar or psychotic disorders
  • current suicidal ideation with plan or intent
  • current moderate or severe substance use disorder not in remission for \>1 mo.
  • severe traumatic brain injury
  • a Montreal Cognitive Assessment (MoCA) indicative of dementia
  • or other disorders that would severely limit study participation

Interventions

BEHAVIORALCognitive Processing Therapy

CPT as described in the treatment manual

BEHAVIORALCognitive Processing Therapy (CPT) + Memory Support

CPT+Memory support will also incorporate frequent and intentional use of strategies to enhance learning and memory of this content.


Locations(1)

Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA

Philadelphia, Pennsylvania, United States

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NCT06000475


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