RecruitingNot ApplicableNCT06000475

Enhancing Memory in CPT for PTSD

Enhancing Memory in Cognitive Processing Therapy for Older Adults With PTSD

Sponsor

VA Office of Research and Development

Enrollment

30 participants

Start Date

Oct 15, 2024

Study Type

INTERVENTIONAL

Conditions

Stress Disorders, Post-Traumatic

Summary

Several psychotherapies for posttraumatic stress disorder (PTSD) have a strong evidence base for their efficacy, but nonresponse rates are high, particularly among older Veterans. Accumulating evidence indicates that memory deficits and poor learning of therapy contents adversely affect psychotherapy treatment response in PTSD. However, limited research has examined methods for increasing learning of therapy contents in psychotherapy for PTSD. The proposed study aims to examine the feasibility of integrating an intervention to increase learning and memory of psychotherapy content into the provision of a widely used psychotherapy, cognitive processing therapy (CPT), for older adults with PTSD. The ultimate goal of this line of research is to develop novel rehabilitation interventions to increase functioning for individuals with PTSD.

Eligibility

Min Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether adding a memory-boosting technique to a standard PTSD therapy (Cognitive Processing Therapy, or CPT) helps older veterans process and recover from traumatic experiences more effectively. **You may be eligible if...** - You are a veteran over 59 years old - You have been diagnosed with PTSD (confirmed by a structured clinical interview) **You may NOT be eligible if...** - You take benzodiazepine medications daily (such as Valium, Xanax, or Ativan), as these affect memory - You have bipolar disorder or a psychotic disorder - You currently have thoughts of suicide with a plan or intent to act on them - You have a moderate or severe substance use disorder (unless you have been in recovery for more than 1 month) - You have had a severe traumatic brain injury - Your cognitive testing suggests dementia Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALCognitive Processing Therapy

CPT as described in the treatment manual

BEHAVIORALCognitive Processing Therapy (CPT) + Memory Support

CPT+Memory support will also incorporate frequent and intentional use of strategies to enhance learning and memory of this content.

Locations(1)

Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA

Philadelphia, Pennsylvania, United States

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NCT06000475

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