RecruitingNCT06005246

Munich ME/CFS Cohort Study

Munich Cohort Study With Biobank for Children, Adolescents, and Young Adults With Post-infection ME/CFS (MUC-CFS)


Sponsor

Technical University of Munich

Enrollment

200 participants

Start Date

Jan 22, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

The Munich cohort study MUC-CFS aims at the characterization and long-term follow-up of myalgic encephalitis/chronic fatigue syndrome (ME/CFS) in young people aged up to 25 years, as well as at the identification of pathomechanisms, biomarkers, and targets for future treatment approaches.


Eligibility

Max Age: 25 Years

Inclusion Criteria4

  • Written consent of the patient (or legal guardian for patients aged \< 18 years).
  • Age 0 - 25 (including)
  • Documented or probable acute infectious disease at the onset of ME/CFS symptoms
  • Diagnosis of ME/CFS according to the IOM criteria, the CCC, the diagnostic worksheet published by P.C. Rowe et al. (2017), or the pediatric case definition published by L.A. Jason et al. (2006).

Exclusion Criteria1

  • • drug/medication abuse, major surgery within the last six months, presence of organ failure, post-stroke/craniocerebral trauma with cognitive deficits, post-intensive care syndrome, syphilis, Lyme disease, AIDS, hepatitis B/C, multiple sclerosis, systemic lupus erythematosus, Sjörgren's syndrome, malignancy, major depression or other severe psychiatric illness, primary sleep disorder, severe endocrine disease (e.g., hypopituitarism, adrenal insufficiency), and other conditions that might explain ME/CFS symptoms.

Locations(1)

MRI Chronic Fatigue Center for Young People (MCFC), Children's hospital, Technical University of Munich (TUM) and Munic Municipal Hospital (MüK)

Munich, Bavaria, Germany

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NCT06005246