RecruitingPhase 2NCT06006559

A Study to Assess the Efficacy, Safety and Pharmacokinetics of EYU688 in Patients With Dengue Fever

A Randomized, Participant- and Investigator-blinded, Placebo-controlled, Parallel Group Study to Assess the Efficacy, Safety and Pharmacokinetics of EYU688 in Patients With Dengue Fever


Sponsor

Novartis Pharmaceuticals

Enrollment

108 participants

Start Date

Feb 20, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to characterize the effect on dengue viral load, fever clearance time as well as on clinical signs and symptoms with the treatment of EYU688 compared with placebo in patients with dengue fever.


Eligibility

Min Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called EYU688 and a drug called Placebo for people with dengue. The study is currently recruiting participants at 23 locations. People eligible for this study include aged 18 Years to 60 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGEYU688

EYU688 administered by oral route

DRUGPlacebo

Matching placebo administered orally as capsules


Locations(24)

Novartis Investigative Site

Manaus, Amazonas, Brazil

Novartis Investigative Site

Brasília, Federal District, Brazil

Novartis Investigative Site

Rio de Janeiro, Rio de Janeiro, Brazil

Novartis Investigative Site

Rio Grande, Rio Grande do Sul, Brazil

Novartis Investigative Site

Sorocaba, São Paulo, Brazil

Novartis Investigative Site

Sao Jose Rio Preto, Brazil

Novartis Investigative Site

Barranquilla, Atlántico, Colombia

Novartis Investigative Site

Bucaramanga, Santander Department, Colombia

Novartis Investigative Site

Cali, Valle del Cauca Department, Colombia

Novartis Investigative Site

Belagavi, Karnataka, India

Novartis Investigative Site

Mumbai, Maharashtra, India

Novartis Investigative Site

Pune, Maharashtra, India

Novartis Investigative Site

Jaipur, Rajasthan, India

Novartis Investigative Site

Chennai, Tamil Nadu, India

Novartis Investigative Site

Kuantan, Pahang, Malaysia

Novartis Investigative Site

Ipoh, Perak, Malaysia

Novartis Investigative Site

Seberang Jaya, Pulau Pinang, Malaysia

Novartis Investigative Site

Miri, Sarawak, Malaysia

Novartis Investigative Site

Kuala Selangor, Malaysia

Novartis Investigative Site

Singapore, Singapore, Singapore

Novartis Investigative Site

Singapore, Singapore

Novartis Investigative Site

Haiphong, Vietnam

Novartis Investigative Site

Hanoi, Vietnam

Novartis Investigative Site

Ho Chi Minh City, Vietnam

View Full Details on ClinicalTrials.gov

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NCT06006559


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