RecruitingNot ApplicableNCT06009523

Effects of Transcranial Direct Current Stimulation (tDCS) in the Management of Suicidal Ideation

Effects of Transcranial Direct Current Stimulation (tDCS) in the Management of Suicidal Ideation in Treatment-resistant Depression : a Pilot Study


Sponsor

Centre Hospitalier Henri Laborit

Enrollment

50 participants

Start Date

Oct 26, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The main objective of this study is to demonstrate that 15 transcranial direct current stimulation (tDCS) sessions of 30 minutes at 2 mA intensity are effective to reduce suicidal ideation


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing whether a non-invasive brain stimulation technique called tDCS (transcranial direct current stimulation — which applies a mild electrical current to the scalp) can help reduce suicidal thoughts in people experiencing a depressive episode. **You may be eligible if...** - You are over 18 - You have been diagnosed with a recurrent or isolated depressive episode - You have been on a stable antidepressant for at least 3 weeks - You have a moderate-to-severe depression score (MADRS ≥20) and measurable suicidal ideation (SSI >3) - You have health insurance coverage - Women must use effective contraception throughout the study **You may NOT be eligible if...** - You have depression with psychosis, schizophrenia, or a history of alcohol or drug dependence - You have already had electroconvulsive therapy (ECT) without improvement this episode - You are currently incarcerated or detained - You have a very high immediate suicide risk (without being hospitalized) - You have metal implants in the brain, a pacemaker, or skin conditions on the stimulation area - You are pregnant, recently gave birth, or are breastfeeding - You are in another interventional study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICETranscranial direct current stimulation

1 stimulation per day during 15 days.


Locations(2)

Centre Hospitalier Nord-Deux-Sèvres

Faye-l'Abbesse, France

Centre Hospitalier Henri Laborit

Poitiers, France

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NCT06009523


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