RecruitingPhase 2Phase 3NCT06011889

Study of the Efficacy and Safety of Etanercept Treatment in Patients With SAPHO Syndrome

A Multicenter, Randomized, Double-blind Clinical Trial Evaluating the Efficacy and Safety of Etanercept Versus Placebo in the Treatment of Patients With SAPHO Syndrome


Sponsor

National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland

Enrollment

60 participants

Start Date

Sep 4, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The study includes adult patients with SAPHO syndrome (ORPHA: 793), meeting the modified classification criteria according to Kahn (2003), with the ineffectiveness of standard treatment (patient's global assessment of the disease on the VAS scale greater than or equal to 4 cm with accompanying pain on the VAS scale greater than or equal to 4 cm) treated with non-steroidal anti-inflammatory drugs in a stable dose for at least 4 weeks and/or classical disease-modifying antirheumatic drugs in stable doses for at least 12 weeks.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Etanercept and a drug called Placebo for people with sapho syndrome. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGEtanercept

treatment with etanercept in addition to NSAID treatment and/or classic Disease Modifying Antirheumatic Drugs

DRUGPlacebo

treatment with placebo in addition to NSAID treatment and/or classic Disease Modifying Antirheumatic Drugs


Locations(1)

Centrum Wsparcia Badań Klinicznych

Warsaw, Masovian Voivodeship, Poland

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06011889


Related Trials