FDG-PET in the Diagnosis of Autoimmune Encephalitis
University of Milano Bicocca
90 participants
Mar 1, 2023
OBSERVATIONAL
Conditions
Summary
The goal of this retrospective observational study is to compare brain fluorodeoxyglucose-positron emission tomography (FDG-PET) of patients with autoimmune encephalitis, normal controls and patients with Alzheimer's disease (AD). The main question it aims to answer is: •is there a specific pattern of brain metabolism in patients with autoimmune encephalitis Participants data and images will be retrospectively collected from hospital records, and FDG-PET images will be analyzed by means of statistical parametric mapping (SPM). Controls will be selected from validated public databases.
Eligibility
Inclusion Criteria5
- Diagnosis of autoimmune encephalitis according to clinical criteria
- Brain magnetic resonance imaging performed between clinical presentation and treatment
- Cerebrospinal fluid analysis performed between clinical presentation and treatment
- Brain FDG-PET performed between clinical presentation and treatment
- Autoantibodies testing performed between clinical presentation and treatment
Exclusion Criteria1
- Refusal to give consent for the study
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Interventions
Brain FDG-PET
Locations(6)
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NCT06019975