RecruitingNCT06033144

Prevalence of Tapia's Syndrome in Weaning Unit

Prevalence of Tapia's Syndrome in Weaning Unit and Associated Factors After Orotracheal Intubation in the ICU

Sponsor

Hopital Forcilles

Enrollment

247 participants

Start Date

Apr 7, 2023

Study Type

OBSERVATIONAL

Conditions

Tapia's Syndrome

Summary

Tapia syndrome is a rare and poorly understood pathology. It is defined by a concomitant attack of the recurrent (branch of X) and hypoglossal (XII) nerves of peripheral or central origin. It is characterized by the paralysis of a vocal cord and the ipsilateral half of tongue. This damage is most often unilateral but it can also be bilateral. It results in dysphonia and swallowing disorders. Tapia syndrome is a rare and poorly understood pathology. To date, less than 100 cases have been described in the literature. Previous works are mainly case reports and literature reviews. No prevalence study has been performed to date. Furthermore, disagreements persist regarding the semiology. Indeed, the involvement of the soft palate is not always described.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This observational study examines the prevalence and characteristics of Tapia syndrome — a rare complication of prolonged intubation that causes paralysis of a vocal cord and one side of the tongue, leading to voice and swallowing difficulties — in patients recovering in a hospital weaning unit after time on a ventilator. Because fewer than 100 cases have been formally documented in medical literature, researchers hope to better define how common the condition is and what factors increase the risk. Adults aged 18 or older who were intubated for more than 48 hours in the ICU and are now admitted to the weaning unit with an alert mental status (Glasgow score ≥ 13) are eligible. Participation involves a clinical assessment of voice and swallowing — no additional tests or interventions are required beyond a physical examination. This summary was generated by AI to help patients understand the study in plain language.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTDiagnosis of Tapia's Syndrome

The diagnostic includes : * Lingual clinical examination * Nasofibroscopy * Ultrasonography

Locations(1)

Hôpital Forcilles

Férolles-Attilly, Seine-et-Marne, France

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NCT06033144