RecruitingNCT06033248

Using Urine Samples to Identify Lung Cancer

Validation and Determination of Feasibility for Clinical Use of an Animal Biosensor Platform to Detect Non-Small Cell Lung Cancer-Specific Volatile Organic Compounds in Urine Samples

Sponsor

Memorial Sloan Kettering Cancer Center

Enrollment

210 participants

Start Date

Aug 24, 2023

Study Type

OBSERVATIONAL

Conditions

Non-small Cell Lung Cancer

Summary

The researchers are doing this study to test the ability of an animal biosensor platform (ABP) to detect NSCLC. Participants in this study will either be diagnosed with NSCLC, suspected to have NSCLC, or have not been diagnosed or suspected to have NSCLC. The ABP test uses laboratory animals that are trained to detect (by smell) different chemicals in urine. Studies show that people with lung cancer have unique chemicals in their urine that are not present in people without lung cancer, and researchers think these chemicals can be used to identify people with lung cancer without the need for invasive procedures (like biopsy).

Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a urine sample can be used to detect early-stage non-small cell lung cancer (NSCLC), potentially offering a simpler, non-invasive alternative to current diagnostic methods. **You may be eligible if...** - You are between 18 and 90 years old - You either have confirmed early-stage NSCLC (stage I–IIIA) that has not been treated yet, OR - You have suspected early-stage NSCLC based on a CT or PET scan, OR - You are confirmed to not have NSCLC **You may NOT be eligible if...** - You are under 18 - You have received cancer treatment (radiation, chemotherapy, surgery, or other) in the past year - You are pregnant - You are taking immune-suppressing medications or have a chronic immune condition - You are missing important clinical staging information Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.