RecruitingNCT06037421

Metagenomic Analysis of Bacterial Microbiota in Breast Milk


Sponsor

Centre Hospitalier Sud Francilien

Enrollment

120 participants

Start Date

Sep 8, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of this study is to determine the extent to which bacteria in the breast milk microbiota represent an infectious risk for premature infants, by investigating whether they possess virulence genes, and if so, whether these are expressed or repressed.


Eligibility

Min Age: 1 Hour

Inclusion Criteria3

  • Women of legal age who have given birth at the CHSF (or in another establishment) and whose newborn(s) are being cared for in the CHSF's Neonatal Medicine and Intensive Care Unit,
  • Women wishing to give their milk to their child,
  • Parents who have given their consent for the mother-child couple to take part in the study.

Exclusion Criteria1

  • Mother having received antibiotic therapy in the 3 months prior to delivery, except for those who received injectable antibiotic prophylaxis during delivery.

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Interventions

OTHERHuman breast milk sampling

Human breast milk sampling

OTHERSaddle sampling

Saddle sampling

OTHERSkin sampling

Skin sampling

OTHERSaliva sampling

Saliva sampling

OTHERblood sampling

blood sampling


Locations(1)

Centre Hospitalier Sud Francilien

Corbeil-Essonnes, France, France

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NCT06037421