Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial

This study is testing whether a structured exercise program can counteract the muscle weakness and frailty (physical decline) that often results from hormone-blocking treatment (androgen deprivation therapy) in men with metastatic prostate cancer. **You may be eligible if...** - You have been diagnosed with metastatic prostate cancer - You are currently on hormone-blocking therapy (androgen deprivation therapy) and expect to continue for at least 4 more months - You have been assessed as frail or pre-frail (scoring 1–5 on the FRAIL scale) - Your doctor has cleared you for exercise - You speak English - You are currently doing less than 2 structured resistance training sessions per week **You may NOT be eligible if...** - You are already very physically active - You have physical or health conditions that prevent safe participation in exercise - You do not speak English Talk to your doctor to see if this trial is right for you.