RecruitingNot ApplicableNCT06043154

Discovering New Insights Into Anorexia Nervosa: Influence of MicrObial DysbiosiS (DIAMOnDS)

Sponsor

Nantes University Hospital

Enrollment

60 participants

Start Date

Feb 22, 2024

Study Type

INTERVENTIONAL

Conditions

Anorexia Nervosa

Summary

This study will investigate the link between the gut microbiota, the occurrence of the central adiposity phenotype, and the patients' fear to regain weight in anorexia nervosa.

Eligibility

Sex: FEMALEMin Age: 15 Years

Inclusion Criteria7

Women
Over 15 years old and 3 months.
Admitted in the specialized department for eating disorders of CHU Nantes for refeeding.
With a diagnosis of anorexia nervosa at admission (restrictive or Binge-Eating-Purging type).
Body Mass Index at admission below 16 kilogram per square meter.
Written informed consent for patients over 18 years old/ oral informed consent from both the patient and a legal representative for patients under 18 years old.
Affiliated with French social security system or beneficiary from such system.

Exclusion Criteria7

Pregnant and breastfeeding women.
Who received a treatment with antibiotic/antifungal (other than local application) in the last three months.
Who had a weight gain in the last month (5% or more of the patient's weight at admission).
Under trusteeship or guardianship.
Not fluent in French
Who participate in another interventional study involving medication.
Patients for whom stool collection or body mass composition analysis (with Dual-energy X-ray absorptiometry) couldn't be done during the first week of hospitalisation.