RecruitingPhase 3NCT06045013

Ultrasound-guided Dextrose Injection Versus Dextrose With Methylprednisolone in Carpal Tunnel Syndrome

Comparison of the Efficacy Between Ultrasound-guided Dextrose Injection Versus Dextrose With Methylprednisolone Injection in Patients With Carpal Tunnel Syndrome: a Prospective, Randomized Double-blind Clinical Trial.


Sponsor

General and Veteran Hospital Croatian Pride Knin

Enrollment

70 participants

Start Date

Sep 13, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this prospective, randomized, double-blinded, head-to-head comparative study is to compare the efficacy of ultrasound-guided 4 ml 5% dextrose perineural injection versus 3 ml 5% dextrose with 1 ml 40 mg/ml methylprednisolone perineural injection in patients with carpal tunnel syndrome (CTS). The main questions it aims to answer are: Is there a difference in efficacy between interventions regarding 1. pain alleviation, 2. improvement in symptoms severity and functional status, 3. improvement in grip strength, 4. size of median nerve cross-sectional area, and 5. improvement in quality of life during the six-month post-intervention follow-up period?


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called 5% dextrose injection and a drug called 5% dextrose injections with methylprednisolone acetate 40 mg/ml for people with carpal tunnel syndrome. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUG5% dextrose injection

Single ultrasound-guided injection of 4 ml 5% dextrose in carpal tunnel via ulnar approach.

DRUG5% dextrose injections with methylprednisolone acetate 40 mg/ml

Single ultrasound-guided injection of 3 ml 5% dextrose with 1 ml 40 mg/ml methylprednisolone acetate in carpal tunnel via ulnar approach.


Locations(1)

General and Veteran Hospital "Croatian Pride" Knin

Knin, Croatia

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NCT06045013


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