RecruitingNot ApplicableNCT06046131

Clinical, Genetic and Environmental Determinants of Prostate Cancer Progression.


Sponsor

Centre Hospitalier Universitaire de la Guadeloupe

Enrollment

3,000 participants

Start Date

Feb 28, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The course and progression of prostate cancer is highly variable, depending on the individual characteristics, the aggressiveness of the disease at the time of diagnosis as well as the ethno-geographic origins of the individuals. The general objective of the project is to identify the clinical, genetic and environmental determinants (risk factors) of the evolution, progression and complications of the disease according to the treatment options. Identifying modifiable and non-modifiable prognostic determinants of disease progression is a major challenge. This knowledge will help guide treatment choices but also, especially in high-risk populations (high incidence of disease) to better tailor prevention policies and possibly screening .


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study investigates how clinical factors, genetics, and environmental exposures influence whether prostate cancer progresses, focusing on men in the French Caribbean and mainland France. **You may be eligible if...** - You are an adult newly diagnosed with prostate cancer - You are being seen at the University Hospital of Guadeloupe or Rennes - You live in Guadeloupe, Martinique, Saint-Martin, or Brittany - You are covered by social security - You have signed the informed consent form **You may NOT be eligible if...** - You have a physical or mental health condition that would prevent you from participating - You are a legally protected adult unable to consent independently Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERStandard care

Extra blood collection for dosages Urine collection for the dosage of non-persistent pollutants, isolation of extracellular vesicles released in urine, analysis of the microbiome, metagenomics to obtain a complete description of the bacterial functions represented as well as other microorganisms present, metabolome profiling and identification and/or assays of any other biological compound of interest strictly related to the specific objectives of the research. Saliva collection for the extraction of the constitutional DNA. An interview using a structured questionnaire A quality of live auto-questionnaire


Locations(2)

CHU of Rennes

Rennes, Ille-et-Vilaine, France

CHU of Guadeloupe

Pointe-à-Pitre, Guadeloupe, Guadeloupe

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NCT06046131


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