Repurposing Valsartan May Protect Against Pulmonary Hypertension

This study tests whether valsartan — a blood pressure medication already widely used — can also help protect against pulmonary arterial hypertension (PAH), a condition where the blood vessels in the lungs become dangerously narrowed and put strain on the heart. **You may be eligible if...** - You are between 18 and 80 years old - You have been diagnosed with WHO Group 1 pulmonary arterial hypertension - Your right heart catheter test confirmed elevated lung artery pressure - You are in NYHA functional class II, III, or IV (mild to severe symptoms) - You can walk at least 50 meters on your own **You may NOT be eligible if...** - You have significant kidney or liver disease - You have dangerously low blood pressure or are pregnant - You are already on medications that interact badly with valsartan (e.g., certain potassium-sparing diuretics or ACE inhibitors in some combinations) - You have had a recent hospitalization for worsening heart failure Talk to your doctor to see if this trial is right for you.