RecruitingNot ApplicableNCT06053684

Non-Invasive Ventilation Versus Neurally-Adjusted Ventilatory Assistance (NAVA) for the Treatment of Bronchiolitis

Comparison of Conventional Non-Invasive Ventilation and Neurally-Adjusted Ventilatory Assistance (NAVA) Non-Invasive Ventilation for the Treatment of Bronchiolitis


Sponsor

Montefiore Medical Center

Enrollment

130 participants

Start Date

Dec 18, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This project aims to answer whether the use of a Neurally-Adjusted Ventilatory Assistance mode for non-invasive ventilation in pediatric patients with bronchiolitis results in improved comfort and reduced escalations in therapy (including intubation) when compared to using a standard mode of non-invasive ventilation. Neurally-Adjusted Ventilatory Assistance (NAVA) has been shown to result in greater synchrony then the standard mode of non-invasive ventilation. The study team hypothesizes that this improved synchrony can result in important clinical improvements when NAVA is used to treat children with bronchiolitis.


Eligibility

Min Age: 0 YearsMax Age: 2 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Neurally-Adjusted Ventilatory Assistance (NAVA) Non-Invasive Mechanical Servo Ventilation and a medical device called Standard Non-Invasive Mechanical Servo Ventilation for people with bronchiolitis. The study is currently recruiting participants at 1 location. People eligible for this study include aged 0 Years to 2 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEStandard Non-Invasive Mechanical Servo Ventilation

The active comparator arm will utilize a standard non-invasive mode to provide ventilation support

DEVICENeurally-Adjusted Ventilatory Assistance (NAVA) Non-Invasive Mechanical Servo Ventilation

The experimental arm will utilize a NAVA mode to provide non-invasive ventilation support


Locations(1)

Children's Hospital at Montefiore

The Bronx, New York, United States

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NCT06053684


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