RY_SW01 Cell Injection Therapy in Active Lupus Nephritis
A Multicenter Phase I/II Clinical Trial to Evaluate the Safety, Tolerability, and Efficacy of RY_SW01cell Injection Therapy in Active Lupus Nephritis
Jiangsu Renocell Biotech Company
60 participants
Aug 17, 2023
INTERVENTIONAL
Conditions
Summary
RY\_SW01 Cell Injection's preclinical research results have shown that the injection significantly improved urine biochemical indicators and tissue damage in two lupus nephritis animal models after MSC administration, with no occurrence of rejection and excellent safety. The mechanism of action of RY\_SW01 Cell Injection is relatively clear, demonstrating favorable therapeutic effects in preclinical animal models. Compared to existing conventional therapies, it has the advantages of "convenient treatment and sustained efficacy." It may help reduce the variety and quantity of drugs administered to patients and the various side effects associated with drug treatment. In some cases, it may even lead to the discontinuation of immunosuppressive drugs, reducing mortality and disability rates while improving the quality of life for patients. Its unique advantages have the potential to fundamentally change the current clinical treatment landscape and offer promising prospects for clinical application.
Eligibility
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Interventions
Injected RY\_SW01 allogonic umbilical cord-derived mesenchymal stem cells(UCMSCs)
Drugs for LN treatment
Locations(1)
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NCT06058078