RecruitingNCT06065514

The Role of Inflammation in Myocardial Infarction

The Complex Role of the Inflammation Response Following an Acute Myocardial Infarction: the INFINITY (INFlammatIoN amI sTudY)


Sponsor

Nicosia General Hospital

Enrollment

120 participants

Start Date

Aug 24, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of this research is to study the prognostic role of a selected combination of cytokines and adipokines in patients with myocardial infarction, as well as to determine their role in the development of adverse cardiac remodeling.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • ACS (ST-ACS, NSTE-ACS, UA) referred for coronary angiography
  • Above 18 years old
  • Consent form obtained

Exclusion Criteria11

  • Chronic Renal Failure (CRF) stage IV (e GFR < 29 ml/min or creatinine > 2 mg/dl)
  • Chronic Liver Disease (CLD) (ALT > 2 times upper normal limit)
  • Chronic Inflammation and/or autoimmune diseases
  • Active Ca
  • Recent CVA (less than 1 month)
  • Recent (within 2 weeks) use of glucocorticoid drugs or immunosuppressive agents
  • Acute or chronic infection, major surgery, or trauma in the last month
  • Previous heart transplantation
  • Poor life expectancy
  • Cardiogenic shock
  • Cardiac arrest

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Locations(4)

Nicosia General Hospital

Nicosia, Cyprus

1st University Department of Cardiology - AHEPA University Hospital

Thessaloniki, Greece

2nd University Department of Cardiology

Thessaloniki, Greece

3rd University Department of Cardiology

Thessaloniki, Greece

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NCT06065514


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