RecruitingNCT06071377

Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)


Sponsor

National Alliance for Sickle Cell Centers

Enrollment

1,000 participants

Start Date

Apr 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The main purpose of this study is to create a longitudinal cohort of those with Sickle Cell Trait (SCT) to better understand the hematologic phenotype for those that carry HbS, assess for differences in those with varying quantities of HbS and assess for potential clinical complications of SCT.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Are willing to voluntarily participate and sign the study consent
  • Know/suspect they have SCT and are willing to get tested to confirm/learn about their SCT status
  • Adults ages 18 and older

Exclusion Criteria4

  • Unwilling to sign consent
  • Known end-stage renal disease or dialysis
  • Known SCD (including sickle cell-beta thalassemia)
  • People who do not have SCT

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Interventions

OTHERBiologic Specimen Collection

Participants will have blood and urine collected at Baseline


Locations(10)

University of Alabama

Birmingham, Alabama, United States

Loma Linda University Health Care

Loma Linda, California, United States

Nemours Children's Hospital

Wilmington, Delaware, United States

Indiana University

Indianapolis, Indiana, United States

Functional Fluidics

Detroit, Michigan, United States

University of North Carolina

Chapel Hill, North Carolina, United States

Duke University

Durham, North Carolina, United States

East Carolina University

Greenville, North Carolina, United States

Nationwide Children's Hospital

Columbus, Ohio, United States

UT Health Houston

Houston, Texas, United States

View Full Details on ClinicalTrials.gov

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NCT06071377


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