RecruitingNot ApplicableNCT06080880

Ondanstron Weekly vs Every 3 Weeks for Prevention of Nausea and Vomiting Induced by Chemotherapy Combined With PD-1 Blockade

Ondanstron Weekly vs Every 3 Weeks for Prevention of Nausea and Vomiting Induced by Chemotherapy Combined With PD-1 Blockade：an Randomized Clinical Trial

Sponsor

Hubei Cancer Hospital

Enrollment

98 participants

Start Date

Dec 1, 2023

Study Type

INTERVENTIONAL

Conditions

Nausea With Vomiting Chemotherapy-Induced

Summary

The aim of this randomized study is to compare the efficacy and safety of ondanstron weekly with every 3 weeks for the prevention of nausea and vomiting induced by chemotherapy combined with PD-1 blockade.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Aprepitant, a drug called Dexamethasone, and others for people with nausea with vomiting chemotherapy-induced. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGOndansetron every 3 weeks

Ondansetron, Po, 24mg/d, 3 days' application every 3 weeks

DRUGAprepitant

aprepitant, Po, 125mg/d, 1day' application every 3 weeks

DRUGDexamethasone

dexamethasone, iv, 10mg/d, 1day' application every 3 weeks

DRUGOndansetron weekly

Ondansetron, Po, 24mg/d, 3 days' application weekly

Locations(1)

Hubei Cancer Hospital

Wuhan, Hubei, China

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NCT06080880

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