RecruitingNCT06086132

Detection and Prevention of Cancer-Related Cardiovascular Toxicity Registry

Detection and Prevention of Cancer-Related Cardiovascular Toxicity Registry (ISACS CARDIONCO-PREDICT)


Sponsor

University of Bologna

Enrollment

10,000 participants

Start Date

May 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This study is being done in order to assess the cardiovascular events known as cardiovascular toxicity of chemotherapy agents and radiotherapy protocols in cancer subjects to identify risk prediction, prevention and treatment of cancer therapy-related cardiovascular toxicity and cancer therapy-related cardiac dysfunction


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Age 18 years old or older
  • Capable of giving informed consent
  • Diagnosis of cancer scheduled for treatment according to treating physician's discretion
  • Life expectancy >1 year
  • For the prospective validation of HFA-ICOS risk score validation: Newly diagnosed breast cancer undergoing treatment with anthracyclines analogues with or without radiotherapy, with or without trastuzumab, or other anticancer drugs

Exclusion Criteria4

  • Age <18 years old
  • Not able to give informed consent
  • Life expectancy <1 year
  • Advanced-stage cancer not eligible for treatment (subjects with an indication of palliative care) according to treating physician's

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Interventions

COMBINATION_PRODUCTProspective validation of the HFA-ICOS risk score in a subset of subjects with newly diagnosed breast cancer and undergoing treatment with anthracyclines analogues with or without radiotherapy

Follow-up visits at baseline, 3-months, and 1-year


Locations(5)

University of Bologna

Bologna, Italy

Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone"

Palermo, Italy

Ss. Cyril and Methodius University in Skopje, University Clinic

Skopje, North Macedonia

University of Belgrade, Clinical Center of Serbia

Belgrade, Serbia

University of Belgrade, Clinical Hospital Center Bezanijska kosa

Belgrade, Serbia

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NCT06086132