Water and Electrolytes Content in HYpertension (WHYSKI) in the SKIn
The Water and Electrolytes Content in Salt-dependent Human HYpertension (WHYSKI) in the SKIn Before and After Surgical Cure of Primary Aldosteronism
University Hospital Padova
35 participants
Jan 1, 2021
OBSERVATIONAL
Conditions
Summary
WHYSKI is a prospective within-patient observational clinical study designed to test the hypothesis that alterations of Na+, K+, water, and the lympho-angiogenetic transcription factor Tonicity Enhancing Binding Protein (TonEBP) mRNA take place in the interstitium of the skin compartment of patients with arterial hypertension due to primary aldosteronism in whom hypertension can be surgically cured.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
Skin biopsies were obtained in all recruited patients.
Video-laparoscopic adrenalectomy in those with unilateral PA. (PA group 1)
Locations(1)
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NCT06090617