Effects of Sufentanil on the Intraoperative Hemodynamics
Effects of Sufentanil on the Intraoperative Hemodynamic Parameters in Patients Undergoing Extracranial-intracranial Bypass Surgery: a Prospective Randomized Controlled Trial
Seoul National University Hospital
92 participants
Nov 24, 2023
INTERVENTIONAL
Summary
This study is a randomized, controlled trial. A total of 92 patients will be randomized to receive sufentanil or remifentanil during extracranial-intracranial bypass surgery.
Eligibility
Inclusion Criteria3
- Patients who undergo elective extracranial-intracranial bypass surgery
- American Society of Anesthesiologists grade 1,2,3
- Age > 18 years old
Exclusion Criteria7
- Refuse to participate to the study
- American Society of Anesthesiologists grade 4
- Body Mass Index < 18.5 kg/m2 or > 35 kg/m2
- Allergic history of opioid
- pregnant
- MAO Inhibitor user
- Severe respiratory insufficiency
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Interventions
Induction: sufentanil TCI 0.3 ng/ml Maintenance: sufentanil TCI 0.05-0.5 ng/ml
Induction: remifentanil TCI 3 ng/ml Maintenance: remifentanil TCI 0.5-5 ng/ml
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06091904