RecruitingNCT06092450

Deep Learning Radiomics Model for Predicting Post-cystectomy Outcome in Muscle Invasive Bladder Cancer

Deep Learning Radiomics Model for Predicting Post-cystectomy Outcome From Preoperative CT in Muscle Invasive Bladder Cancer


Sponsor

First Affiliated Hospital of Chongqing Medical University

Enrollment

500 participants

Start Date

Aug 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

Muscle invasive bladder cancer (MIBC) has a poor prognosis even after radical cystectomy. Postoperative survival stratification based on radiomics and deep learning may be useful for treatment decisions to improve prognosis. This study was aimed to develop and validate a deep learning radiomics model based on preoperative enhanced CT to predict postoperative survival in MIBC.


Eligibility

Inclusion Criteria3

  • patients with pathologically confirmed MIBC after radical cystectomy;
  • contrast-CT scan less than two weeks before surgery;
  • complete CT image data and clinical data.

Exclusion Criteria4

  • patients who received neoadjuvant therapy;
  • non-urothelial carcinoma;
  • poor quality of CT images;
  • incomplete clinical and follow-up data.

Interventions

OTHERdevelop and validate a deep learning radiomics model based on preoperative enhanced CT image

develop and validate a deep learning radiomics model based on preoperative enhanced CT to predict postoperative survival in MIBC


Locations(1)

Department of Urology, The First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China

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NCT06092450


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