RecruitingNot ApplicableNCT06102382

The Effect of Two Different Doses of Noradrenaline on Hypotension Caused by Spinal Anesthesia for Cesarean Section


Sponsor

Assiut University

Enrollment

100 participants

Start Date

Sep 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

To compare two infusion rates of norepinephrine for prophylaxis against post-spinal hypotension during caesarean delivery.


Eligibility

Sex: FEMALEMin Age: 19 YearsMax Age: 40 Years

Inclusion Criteria2

  • Pregnant women scheduled for cesarean section under spinal anesthesia
  • Gestational age of at least 37 weeks

Exclusion Criteria7

  • Patient refusal
  • Contraindications of spinal anesthesia
  • Allergy to the study drug
  • Height\<150 cm, weight \< 60 kg, body mass index (BMI) ≥40 kg/m2.
  • patients with cardiac morbidities
  • Hypertensive disorders of pregnancy.
  • Prepartum hemorrhage

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Interventions

DRUGNorepinephrine (0.1)

An intravenous bolus dose of norepinephrine (5 µg) followed by infusion of 0.1 µg/kg/min till 5 minutes after delivery of the fetus.

DRUGNorepinephrine (0.075)

An intravenous bolus dose of norepinephrine (5 µg) followed by infusion of 0.075 µg/kg/min till 5 minutes after delivery of the fetus.


Locations(1)

Assiut University Woman Health Hospital

Asyut, Egypt

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