RecruitingNot ApplicableNCT06104072

Effect of Adding Computerized Cognitive Training on Balance, Locomotion and Cognition in Parkinson's Disease

Adding Computer-based Cognitive Training to Conventional Rehabilitation Can Affect Postural Stability , Locomotion and Cognition in Parkinson's Disease Patients

Sponsor

Engy Badreldin Saleh Moustafa, PhD

Enrollment

70 participants

Start Date

May 23, 2024

Study Type

INTERVENTIONAL

Conditions

Parkinson Disease

Summary

BACKGROUND: Postural instability and gait abnormalities are cardinal features in Parkinson's disease (PD). It represents one of the most disabling symptoms in the advanced stages of the disease. The purpose of this study was to evaluate the immediate and long-term effects of adding computer-based cognitive training to physical therapy interventions on postural stability, locomotion, and cognitive performance in Parkinson's disease patients.

Eligibility

Min Age: 58 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether adding computerized brain training exercises to standard physical therapy can improve balance, walking, and thinking abilities in people with mild-to-moderate Parkinson's disease who also show early signs of cognitive decline. **You may be eligible if...** - You are an Egyptian patient diagnosed with Parkinson's disease, aged 58–68 - You have had Parkinson's disease for 2–5 years - You have mild-to-moderate disease severity (Hoehn and Yahr stage 2.5 or 3) - You show mild cognitive impairment (specific test scores required) - You can walk on your own and are otherwise medically and psychologically stable **You may NOT be eligible if...** - Your parkinsonism is caused by medication, trauma, or infection (not idiopathic) - You have severe speech, hearing, or vision problems - You have a pacemaker or metallic implants in your body - You have had seizures, head injury, or brain surgery - You have serious heart or lung conditions - You have severe arthritis or other major joint/limb problems - You are currently taking cognitive-enhancing medications (e.g., rivastigmine, memantine) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEREHACOM Software

It is a computer-based cognitive rehabilitation test that includes 32 cognition training tasks for attention/concentration, reaction behavior, memory , logical reasoning \& executive functioning with graded difficulty . It is composed of regular PC , 1G RAM , DVD drive, 100 GB hard drive with windows XP SP3, 128 MB RAM direct 3D graphic card , Screen at least 19" , regular PC keyboard or Rehacom panel \& printer .The Rehacom software version is (patientenpult (1990-1997) EN/ISO-13485-certified). * For each Cognitive training domain there is one hundred levels of difficulty. * Each patient is evaluated from level one(1) ang gradually increase the difficulty till we reach the level that will be used in the treatment sessions as the patient's performance improve we can proceed to the next level. * The period of the session was chosen to be maximum (60 minutes) for each patient with five minutes rest in between each level.

OTHERA Designed Physical Therapy Program

A designed physiotherapy program consisted of aerobic exercise on treadmill, stretching exercise, Proprioceptive neuromuscular facilitation (PNF) techniques, Graduated active exercises, postural correction, gait training, balance training on different base of supports using static and dynamic balance training with reciprocal and weight shifting exercises.