RecruitingNot ApplicableNCT06108336

Cerebellar Involvement in Cognitive Sequencing

Investigation of Cerebellar Involvement in Cognitive Sequencing


Sponsor

Johns Hopkins University

Enrollment

50 participants

Start Date

Mar 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Although there is increasing recognition that the cerebellum is involved in cognition as well as motor function, the manner in which the cerebellum contributes to cognition is uncertain. One theory that might account for both motor and cognitive contributions of the cerebellum is that the cerebellum is involved in sequencing of relevant events or stimuli. Previous experiments have suggested that disruption of the cerebellum impairs the prediction of the next event in a sequence. The present experiment will examine the impact of cerebellar stimulation on brain activation during the performance of both sequence-demanding and non-sequence-demanding tasks.


Eligibility

Min Age: 18 YearsMax Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called No TMS during non-sequence-demanding task, a procedure called No TMS during sequence-demanding task, and others for people with effects of cerebellar stimulation on brain activation. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 50 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURETMS during sequence-demanding task

TMS is administered during the execution of sequence-demanding task. Transcranial magnetic stimulation (TMS) is a safe and non-invasive technique for transiently modulating brain activity

PROCEDURENo TMS during sequence-demanding task

TMS is not administered during the execution of sequence-demanding task.

PROCEDURETMS during non-sequence-demanding task

TMS is administered during the execution of non-sequence-demanding task. Transcranial magnetic stimulation (TMS) is a safe and non-invasive technique for transiently modulating brain activity

PROCEDURENo TMS during non-sequence-demanding task

TMS is not administered during the execution of non-sequence-demanding task


Locations(1)

Johns Hopkins University School of Medicine

Baltimore, Maryland, United States

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NCT06108336