Prevention of Frailty With Fisetin and Exercise in Breast Cancer Survivors

This study tests whether a natural plant compound called fisetin, combined with exercise, can prevent frailty and physical decline in postmenopausal women who have survived early-stage breast cancer. Frailty is a common side effect of cancer treatment that makes people weaker and more vulnerable. **You may be eligible if:** - You are a postmenopausal woman (either naturally or through treatment) - You have been diagnosed with early-stage breast cancer (stage I or II) - You have completed primary cancer treatment - You show signs of physical frailty or pre-frailty - You are 18 or older **You may NOT be eligible if:** - You are currently on cytotoxic chemotherapy - You have advanced (metastatic) breast cancer - You have certain other serious health conditions - You are taking certain medications that could interact with fisetin Talk to your doctor to see if this trial is right for you.