Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma, PAP-OP Study

This study (PAP-OP) screens women for HPV-related precancerous changes in the genital area. It focuses on two groups: women who themselves have HPV-positive throat cancer (oropharyngeal squamous cell carcinoma), and female partners of male patients with the same diagnosis. HPV can spread between partners and cause different cancers. **You may be eligible if:** - You are a woman 18 or older - You are a female patient at Mayo Clinic who has been diagnosed with HPV-positive throat cancer, OR - You are the female partner of a Mayo Clinic patient diagnosed with HPV-positive throat cancer - You are willing to complete questionnaires and give blood/saliva samples **You may NOT be eligible if:** - The oropharyngeal cancer is HPV-negative - You are unable to give informed consent - You are unwilling to attend a screening visit at Mayo Clinic Talk to your doctor to see if this trial is right for you.