RecruitingNot ApplicableNCT06121089

Local Cecal Cancer - Optimization of Surgical Treatment

Study of the Oncological Outcomes of Ileocecal Resection With D3 for Cecal Cancer


Sponsor

Moscow Clinical Scientific Center

Enrollment

200 participants

Start Date

Sep 1, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to determine the clinical efficacy, safety, and oncologic outcomes of ileocecal resection (ICR) with D3 lymphadenectomy compared to standard right hemicolectomy(RHC) for cecal cancer.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study compares different surgical approaches for treating localized cancer of the cecum (the beginning of the large intestine), with the goal of finding the best surgical strategy to remove the cancer and nearby lymph nodes while minimizing complications. **You may be eligible if...** - You are 18 years old or older - You have been confirmed to have colon adenocarcinoma (the most common form of colon cancer) - Your cancer is at clinical stage T1–T3, with lymph node involvement (N+) and no distant spread (M0) - You are well enough to undergo surgery **You may NOT be eligible if...** - You have another active or recent cancer - Your tumor has grown beyond the colon wall (stage T4 or higher) - Your cancer has spread to other parts of the body (metastatic) - Your tumor is causing a blockage or perforation requiring emergency surgery - You have already received chemotherapy before surgery (neoadjuvant chemotherapy) - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREileocecal resection with extended D3 lymphadenectomy.

Laparoscopy ileocecal resectionith extended D3 lymphadenectomy including 201, 202, 203 and 213 groups of lymph nodes. Manual double-row ileo-ascendo-anastomosis.

PROCEDURERight hemicolectomy with D3 lymphadenectomy.

Laparoscopy right hemicolectomy with D3 lymphadenectomy including 201, 202, 203, 213, 211, 212, 221, 222-rt groups of lymph nodes. Manual double-row ileo-transverse-anastomosis.


Locations(1)

Moscow Clinical Scientific Center

Moscow, Russia

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NCT06121089


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