Diagnostic Performance of [18F]PSMA-1007 PET/CT Imaging in Patients With Newly-Diagnosed Prostate Cancer

This study evaluates a specialized type of PET scan — using a tracer called [18F]PSMA-1007 — to see whether it can more accurately detect whether prostate cancer has spread to nearby lymph nodes before surgery, compared to standard CT and MRI imaging. **You may be eligible if...** - You are a male patient 18 or older with newly diagnosed, biopsy-confirmed prostate cancer - Your cancer is classified as at least high-risk (grade group 4 or 5, or PSA above 20, or stage T3a or higher) - You are planning to have surgery (radical prostatectomy with full lymph node dissection) - You have completed standard imaging (CT or MRI) within the past 60 days **You may NOT be eligible if...** - You have already received any treatment for prostate cancer (surgery, radiation, or medication) - You have an allergy or contraindication to [18F]PSMA-1007 - You cannot tolerate a PET-CT scan (due to weight, claustrophobia, or inability to lie still) - You have previously had PSMA-targeted PET imaging Talk to your doctor to see if this trial is right for you.