Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging
Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging Among Mid-Life Adults: Phase II
University of Kansas Medical Center
160 participants
Feb 23, 2024
INTERVENTIONAL
Conditions
Summary
The goal of this behavioral clinical trial is to learn how to increase physical activity in mid-life adults. Specifically, can guided imagery that includes creating mental pictures increase excitement about working out. Participants will be asked to complete testing at the beginning of the study, following 6-weeks of an in-person exercise program, and 6-weeks after finishing the exercise program. Testing will include an exercise test, MRI, questionnaires, computer tasks, and a blood draw.
Eligibility
Inclusion Criteria11
- speak English
- have access to reliable communication (a telephone or cell phone, computer, etc.)
- normal or corrected to normal vision and hearing
- ambulatory (without the use of assistive devices)
- physically underactive
- able to give informed consent
- able to exercise continuously on the recumbent stepper exercise device for 4 minutes greater than or equal to 25 watts to demonstrate ability to perform exercise on stepper \& no aerobic exercise contraindications or other safety/physical concerns
- able to communicate with investigators, follow 2-step command \& correctly answer consent comprehension questions
- stable blood pressure and statin medication doses for 30 days as these affect vascular health/hemodynamics
- willing and able to safely enter magnetic resonance (MR) scanner and attempt the MR scan
- willing and able to attempt a blood draw
Exclusion Criteria4
- patients with arrhythmias or acute cardiac events will be excluded due to potential complications with the supervised moderate exercise
- at risk for hazard due to magnetic fields due to MR safety concerns
- have any neurologic or psychiatric disorder except depression, anxiety (including post-traumatic stress disorder)
- have history of seizures or head trauma due to MR data quality
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
During the audio recorded guided imagery exercise participants will be asked to think in detail of a future (6 months to a year) where they have made healthy choices regarding physical activity and are physically active.
During the audio recorded guided imagery exercise participants will be asked to think about a routine weekly activity.
During the audio recorded guided imagery exercise participants will be asked to think in detail about the positive outcomes and sensations associated with an exercise bout.
During the audio recorded guided imagery exercise participants will be asked to think in detail about the physical sensations associated with an exercise bout.
The high intensity interval training (HIIT) will be conducted 2 times per week for 6 weeks. The duration of each individual exercise session will last about 45 minutes. After the 5-minute warm-up at 30% peak workload, HIIT will consist of repeated 1-minute high intensity bursts ("on" interval) alternated with 1-minute interval recovery ("off" interval) for 25 minutes. The "on" interval will begin at 80% of peak watts (range: 75%-85%) followed by the "off" interval at 10% of peak watts. The session will end with up to 10 minute cool-down at 20% peak workload.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06123182