RecruitingNCT06135571

Study on the No.253 Lymph Node Metastasis Patterns in Left-Sided Colon and Rectal Cancer

Real World Registry Study on the No.253 Lymph Node Metastasis Patterns in Left-Sided Colon and Rectal Cancer


Sponsor

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Enrollment

3,000 participants

Start Date

Sep 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to learn about the the pattern of metastasis of the No.253 lymph node in colorectal cancer. The main questions it aims to answer are: 1. What are the risk factors for metastasis to the No.253 lymph node? 2.What is the prognosis for patients with metastasis to the No.253 lymph node? Patients with descending colon cancer, sigmoid colon cancer, and rectal cancer who undergo curative surgery with dissection of the No.253 lymph node are included in this study


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria4

  • Age: 18-75 years;
  • Underwent laparoscopic left hemicolectomy, sigmoid colectomy, or rectal cancer radical surgery.
  • Postoperative pathology confirmed as adenocarcinoma.
  • No evidence of distant metastasis.

Exclusion Criteria6

  • Previous history of malignant colorectal tumors.
  • Patients who have undergone multiple abdominal-pelvic surgeries.
  • Patients undergoing emergency surgery due to complications such as intestinal obstruction, intestinal perforation, or intestinal bleeding.
  • Surgery did not achieve R0 resection.
  • Patients with concurrent other malignant tumors or multiple primary colorectal cancers.
  • Patients unwilling to sign an informed consent or follow the study protocol for follow-up.

Interventions

PROCEDURELaparoscopic colorectal surgery

Patients underwent laparoscopic left colectomy, sigmoid resection or rectal surgery according to the location of tumor.


Locations(4)

Peking Union Medical College Hospital

Beijing, Beijing Municipality, China

China-Japan Friendship Hospital

Beijing, Beijing Municipality, China

Beijing Cancer Hospital

Beijing, Beijing Municipality, China

Chinese PLA General Hospital

Beijing, Beijng, China

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NCT06135571


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