GCS Survey: "GHB IN CHEMICAL SUBMISSION: MYTH OR REALITY?"
Assistance Publique - Hôpitaux de Paris
200 participants
Mar 20, 2024
OBSERVATIONAL
Conditions
Summary
According to the media, GHB is the main substance used for chemical submission. The national survey conducted by the Addictovigilance centre of Paris on drug-facilitated assaults shows that GHB is used, but only in a very small proportion of cases. However, the short detection times for this substance point to its possible under-detection (06-09h in blood, 10-12h in urine). A pilot research protocol in Ile de France focusing on capillary analysis is therefore being proposed to volunteer victims to overcome this bias and answer this question: is the massive use of GHB in chemical submission a myth or a reality?
Eligibility
Inclusion Criteria6
- Victims over the age of majority (≥ 18 years) on the day of the alleged events
- With a medical history leading to the suspicion of chemical submission:
- Presence of evocative clinical signs (amnesia and/or behavioural disorders and/or neurological disorders and/or other somatic disorders, etc.) AND
- In the presence of potential criminal acts (suspected or proven assault or attempted assault).
- French speaking
- Having been informed of the search
Exclusion Criteria9
- \- Victims who were minors (<18 years) on the day of the alleged events.
- Victims who usually use GHB/GBL recreationally.
- Suspecting administration of a harmful substance with no crime or offence committed at the time and no attempted assault
- Victims of needle spiking
- Victims with very short hair (<3 cm), bald or shaven heads
- Victims who have exceeded the maximum time limit for taking a hair sample (6 months after the event)
- Do not speak French
- Oppose to participating in the study
- Victims presenting a psychotic or cognitive syndrome likely to impair judgement Victims placed under guardianship or legal protection (article L11-22-2 CSP)
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Interventions
Samples taken between 2 and 6 months after the presumed events. A pre-analytical treatment of the hair (washing, fragmentation), followed by detection by high-resolution mass spectrometry is carried out by an expert laboratory to search for both GHB and psychoactive drugs.
Locations(3)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06137599