RecruitingNot ApplicableNCT06138106

Developing a Nutritional Supplement to Increase Collagen Synthesis in People


Sponsor

University of California, Davis

Enrollment

20 participants

Start Date

Nov 21, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to test whether a natural product supplement can potentiate the increase in collagen synthesis following the ingestion of collagen protein. The investigators have developed a model of natural (GRAS certified) products that stimulate collagen synthesis, in vitro. The investigators will determine whether the natural product supplement can potentiate the collagen synthetic response to the ingestion of collagen protein. Basal and fed serum will be isolated and these samples will be used to treat human engineered ligaments.


Eligibility

Min Age: 18 YearsMax Age: 30 Years

Inclusion Criteria1

  • Young healthy adults (18-30 y)

Exclusion Criteria3

  • Pregnancy
  • Smoking
  • Receiving any medication that may interfere with the study outcomes

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Interventions

DIETARY_SUPPLEMENTNatural Product Supplement

Participants will have blood drawn before and one hour after consuming the natural product supplement. For 7-days the participants will perform load-bearing exercise and consume the supplement. On the final day, blood will be collected 4 hours after the final exercise bout.

DIETARY_SUPPLEMENTPlacebo control

Participants will have blood drawn before and one hour after consuming the placebo supplement. For 7-days the participants will perform load-bearing exercise and consume the supplement. On the final day, blood will be collected 4 hours after the final exercise bout.


Locations(1)

Hickey Laboratory

Davis, California, United States

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NCT06138106


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