RecruitingPhase 2NCT06141447
Changes in Hemorrhage With Prophylactic Oxytocin for Dilation and Evacuation
Changes in Rate of Hemorrhage With Prophylactic Oxytocin for Second Trimester Dilation and Evacuation in the Clinic Setting
Sponsor
University of Colorado, Denver
Enrollment
150 participants
Start Date
May 2, 2024
Study Type
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to assess the effectiveness of prophylactic oxytocin on hemorrhage rates for second trimester dilation and evacuation (D\&E) in the clinic setting.
Eligibility
Sex: FEMALEMin Age: 18 YearsMax Age: 55 Years
Inclusion Criteria2
- clinic-based D\&E at 18 weeks gestational age and above
- speaks English or Spanish
Exclusion Criteria8
- refuses IV
- history of coagulopathy
- anticoagulant use in the preceding five days
- chorioamnionitis or sepsis
- suspected placenta accreta spectrum
- intrauterine fetal demise
- multiple gestation
- use of misoprostol for cervical preparation
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
DRUGOxytocin + normal saline
40 units IV oxytocin once in a 1000 mL bag of normal saline
DRUGNormal saline
1000 mL bag of normal saline alone
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06141447
Related Trials
CLOT-LESS - CLOsure Tailored: LEss Antithrombotic Strategy After LAAC for Stroke Prevention
NCT075758671 location
Onyx™ Liquid Embolic IDE Clinical Study
NCT0674280116 locations
SWIFT - SWIss Factor XIII Trial in PPH
NCT064819959 locations
U-CaVIT Versus Standard of Care for Prevention of Atonic Postpartum Hemorrhage After Cesarean Section in High-risk Women.
NCT070196231 location
CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial
NCT0595834214 locations